Use variable for column name in SQL statement

Is it somehow possible to use a variable for the column name in a SQL UPDATE statement?

e.g

UPDATE TABLE_1
SET TABLE_1.:columnName = value1
WHERE TABLE_1.:columnName = some_value;

but like this I jsut get a Syntax error. "columnName" is incorrect or misplaced

The reason is, I want to update iterative Column 1 to n.