HI .
You can send 997 for your inbound 850/846.
to achieve this.
1. in EDI Separater Receiver CC you need to enable the 997 as mentioned below.
2. you need to create one more ICO for EDI Separater sender CC to send the 997. and here you need to maintain EDI Partner ID in " interchange receiver ID Qualifirer " parameter. as mentioned below.
Best regards.
Ramesh